D-57
Nov. 03 - 05, 2026
| Date & Time | Nov 3, Tuesday |
| 09:00 | Registration |
| 10:30-11:00 | Opening Remarks |
| 11:00-12:30 | Session 1. Senescence, Metbolism, and Tissue Regeneration Chair |
|
-An Integrative Single-Cell and Orthogonal Senolytic Strategy Reveals Targetable Senescent Fibroblasts in the Lung
Makoto Nakanishi (University of Tokyo, Japan) -Defying the Clock: Divergent Stress Responses in Salamander, Mouse, and Human Maximina Hee Yun (Chinese Institutes for Medical Research / Technische Universität Dresden, China/Germany) -Identifying specific functional roles for senescence across cell types in diseases Bin Zhou (Chinese Academy of Sciences/China) - TBA |
|
| 12:30-14:00 | Lunch & Poster Session |
| 14:00-15:00 | Keynote Lecture 1 Chair |
| 14:00-15:00From Basic Discovery to Healthy Aging Guanghui Liu (Chinese Academy of Sciences, China) | |
| 15:00-16:00 | Flash Talk |
| 16:00-16:20 | Coffee Break |
| 16:20-18:00 | Session 2. Senescenence Heterogeneity, Microenvironment, and Cancer Chair |
|
-Calcium Channel Blockers as a new class of senolytics Marco Demaria (ERIBA/UMCG, Netherlands) -Cellular senescence: how many, how deep, how bad, and how to tackle? Clemens A. Schmit (Johannes Kepler University Linz(JKU) / Max Delbrück Center / Charité-Universitätsmedizin Berlin, Austria/Germany) -Targeting NAD+ metabolism for senolysis and systemic benefits Peter D. Adams (Sanford Burnham Prebys Medical Discovery Institute, USA) -Targeting senescent cells reverses menopause-associated metabolic decline Gerardo Ferbeyre (Université de Montréal, Canada) - TBA (TBA) |
|
| 18:30 | Welcome Reception |
| Date & Time | Nov 4, Wednesday |
| 09:00-11:00 | Session 3. Molecular Mechanisms of Cellular Senescence Chair |
|
-Tissue-Specific Cancer Susceptibility During Ageing: Insights from Autophagy-Hypomorphic Mice Masashi Narita (Cambridge University, UK) -How mitochondria shape the SASP João F. Passos (Mayo Clinic, USA) -An Opportunistic Transcriptional Regulatory System in Senescence Chanhee Kang (Seoul National University, South Korea) -Metabolic Dysregulation in Senescent Cells and Their Roles in the Tumor Akiko Takahashi (Japanese Foundation for Cancer Research , Japan) - TBA |
|
| 11:00-11:30 | Coffee Break |
| 11:30-12:30 | Keynote Lecture 2 Chair |
| 11:30-12:30Targeting the intersection between senescence and cancer Scott W. Lowe (Memorial Sloan Kettering Cancer Center (SKI), USA) | |
| 12:30-14:00 | Lunch & Poster Session |
| 14:00-16:00 | Session 4. Genome Stability, DNA Damage, Cell Fate, and Senescence Chair |
|
-A systemic metabolic axis controlling chondrocyte senescence and osteoarthritis Jin-Hong Kim (Seoul National University, South Korea) -Post-transcriptional Regulation of Transcription Factors Governing Cell Cycle Arrest in Cellular Senescence Young-Sam Lee (DGIST, South Korea) -Deciphering Aging Mechanisms and Developing Interventions Based on Digital Twins Weiqi Zhang (Chinese Academy of Sciences, China) -Same old senescence? how context shapes function Han Li (Pasteur Institute, France) |
|
| 16:00-16:30 | Coffee Break |
| 16:30-18:00 | yICSA Event |
| 19:00 | Gala Dinner |
| Date & Time | Nov 5, Thursday |
| 09:00-11:00 | Session 5. Senotherapeutics and Healthy Aging Chair |
|
-Senescence as a modifiable driver of metastasisDarren J. Baker (Mayo Clinic, USA) - Laura J. Niedernhofer (University of Minnesota, USA) -Extracellular Aging Signals Drive Senescence Propagation Okhee Jeon (Korea University, South Korea) -Cellular Senescence and Human Longevity: Implications for Senotherapy Yousin Suh (Columbia University, USA) - TBA |
|
| 11:00-11:30 | Coffee Break |
| 11:30-12:30 | Closed Session |
